Of course one will.
When is the question.
Right now Calgary stands head and shoulders above the others north of the 43rd. Right now though they have a fairly old core to work with. Iginla is 32, Jokinnen is 30, Lankow is 32, Conboy is 37, there defense is in better shape with the oldest player being 31, but as they currently stand their window is narrow.
After them... well it get's interesting. Just by virtue of who their GM is, the Leafs are probably the most likely to win the Cup in the east, but none of the teams in the east look to have a good chance of even making the playoffs this season.
Vancouver probably has the second best shot to win if they can retain Luongo. Admittedly I don't see them all that often, but they may need to see if they can find a defenseman who is one of those game changers. I don't recall seeing anyone who clearly dominated the ice when he played. Granted there are only about a half dozen of those playing right now.
Edmonton I also don't see much, but they aren't all that close. They were 18th in goals for last year, and 22nd in goals against. They have a reasonably you group, of forwards but their blueline outlook isn't as rosy. Souray is 33 and eats the most ice time, Visnosky is also 33 and second in ice time, third and fourth are fine, but the fifth guy is Staios at 36. That's a lot of experience that is likely to be on the decline, out of the game by the time their forwards mature.